Search results for "Autonomic blockade"

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Influence of digoxin on sinus node function after pharmacologic autonomic blockade.

1983

The effect of iv digoxin on normal sinus node function was studied after pharmacologic autonomic blockade (AB) in ten patients. Sinus cycle length (SCL), sinus node recovery time (SNRT) and sinoatrial conduction time (SACT) were determined before and after AB with propranolol (0.2 mg/kg body weight) and atropine sulfate (0.04 mg/kg body weight) iv, and 15 min, 30 min, and 45 min after 1 mg iv digoxin. AB resulted in a significant decrease (P less than 0.01) in SCL (916 +/- 158 to 716 +/- 120 ms), in SNRT (1,229 +/- 221 to 871 +/- 190 ms), and in SACT (79 +/- 34 to 44 +/- 10 ms). Fifteen minutes after iv digoxin there was no significant change observed in SCL (716 +/- 120 to 708 +/- 92 ms), …

AdultAtropineMaleDigoxinDigoxinPropranololTherapeutic indexDrug DiscoveryAutonomic blockademedicineAtropine sulfateHumansCycle lengthGenetics (clinical)AgedSinoatrial NodeChemistryGeneral MedicineMiddle AgedPropranololSinus node functionAnesthesiaMolecular MedicineFemalemedicine.drugSinoatrial conductionKlinische Wochenschrift
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Supernormal conduction in the right bundle branch: lack of influence of autonomic blockade.

1984

A programmed atrial stimulation at a driving rate of 100/min was performed in a 47-year-old woman with left bundle branch block. Supernormal conduction lasting 40 ms was revealed within the right bundle branch. After autonomic blockade (0.2 mg propranolol/kg body weight and 0.04 mg atropine/kg body weight) the position and duration of the supernormal conduction did not change. This suggests that the autonomic nervous system has no influence on the supernormal phase of conduction in the human intraventricular conduction system.

Atropinemedicine.medical_specialtyBundle of HisSupernormal conductionBundle-Branch BlockPropranololHeart Conduction SystemInternal medicineDrug DiscoveryAutonomic blockademedicineHumansRight bundle branchGenetics (clinical)Bundle branch blockbusiness.industryLeft bundle branch blockGeneral MedicineMiddle Agedmedicine.diseasePropranololAutonomic nervous systemAtropineAnesthesiaCardiologyMolecular MedicineFemalebusinessmedicine.drugKlinische Wochenschrift
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